Sulfotransferase family 1E , estrogen-preferring , member 1(CPTC-SULT1E1-1) , Biotin conjugate , 0.1mg / mL

The soluble sulfotransferases contribute to the elimination of xenobiotics , the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1 , also known as STE , is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine , liver and kidney , SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer , suggesting a role for SULT1E1 in tumorigenesis. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.