ARF1 (Golgi Apparatus Marker)(ARF1/2117) , 1mg / mL

The ADP-ribosylation factor (ARF) family comprises a group of structurally and functionally conserved proteins , which are members of the Ras superfamily of regulatory GTP-binding proteins. The ARF family is divided functionally into the ARF and the ARF-like proteins. ARF's share more than 60% sequence identity , appear to be ubiquitous in eukaryotes , and are highly conserved evolutionarily. ARF is involved in intracellular protein traffic to and within the Golgi complex. ARF has a number of disparate activities including maintenance of organelle integrity , assembly of coat proteins , as a co-factor for cholera toxin and as an activator of phospholipase D. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.