ALPL antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : There are at least four distinct but related alkaline phosphatases : intestinal, placental, placental-like, and liver/bone/kidney(tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any partic µLar tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. ALPL(Alkaline phosphatase, tissue-nonspecific isozyme) is also named as AP-TNAP, TNSALP and belongs to the alkaline phosphatase family. It can exsit as a homodimer with the molec µLar weight of 140 kDa(PMID : 18724009). ALPL was syntheVolumed as a 66-kDa endo-b-N-acetylglucos-aminidase H(Endo H)-sensitive form, and processed to an 80-kDa mature form, which is anchored to the plasma membrane via glycosylphosphatidylinositol(GPI)(PMID : 10839996).This antibody can bind the four mentioned alkaline phosphatases.
Immunogen : alkaline phosphatase, liver/bone/kidney
Aliases : Alkaline phosphatase, Alkaline phosphatase liver/bone/kidney isozyme, Alkaline phosphatase tissue nonspecific isozyme, ALPL, BLAP, Bone Alkaline Phosphatase, NBAP
Observed MW : 60-80 kDa
Uniprot ID : P05186
Reactivity : Human
Application : ELISA, WB, IHC, FC
Recommended dilution : WB : 1 : 500-1 : 3000; IHC : 1 : 20-1 : 200
Gene ID : 249
Research Area : Stem Cells, Cell Division and Proliferation, Metabolism, Developmental biology

Référence interne: FNab00347