AMPK gamma 1 antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background : The protein encoded by this gene is a reg µLatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cell µLar energy status. In response to cell µLar metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in reg µLating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma reg µLatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Immunogen : protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Aliases : AMPK gamma1 AMPK subunit gamma 1 AMPKG, PRKAG1
Observed MW : 38 kDa
Uniprot ID : P54619
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IF
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 50 - 1 : 200; IF : 1 : 50 - 1 : 100
Gene ID : 5571
Research Area : Cardiovasc µLar, Metabolism, Developmental biology, Signal Transduction

Référence interne: FNab00379